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The landscape of the A-to-I RNA editome from 462 human genomes

A-to-I editing, as a post-transcriptional modification process mediated by ADAR, plays a crucial role in many biological processes in metazoans. However, how and to what extent A-to-I editing diversifies and shapes population diversity at the RNA level are largely unknown. Here, we used 462 mRNA-seq...

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Detalles Bibliográficos
Autores principales: Ouyang, Zhangyi, Ren, Chao, Liu, Feng, An, Gaole, Bo, Xiaochen, Shu, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089959/
https://www.ncbi.nlm.nih.gov/pubmed/30104667
http://dx.doi.org/10.1038/s41598-018-30583-7