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Understanding the biology of HER3 receptor as a therapeutic target in human cancer

HER3 belongs to the human epidermal growth factor receptor (HER) family which also includes HER1/EGFR/erbB1, HER2/erbB2, and HER4/erbB4. As a unique member of the HER family, HER3 lacks or has little intrinsic tyrosine kinase activity. It frequently co-expresses and forms heterodimers with other rec...

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Detalles Bibliográficos
Autores principales:	Lyu, Hui, Han, Amy, Polsdofer, Erik, Liu, Shuang, Liu, Bolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090011/ https://www.ncbi.nlm.nih.gov/pubmed/30109175 http://dx.doi.org/10.1016/j.apsb.2018.05.010

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