Epigenetic modification in histone deacetylase deletion strain of Calcarisporium arbuscula leads to diverse diterpenoids

Epigenetic modifications have been proved to be a powerful way to activate silent gene clusters and lead to diverse secondary metabolites in fungi. Previously, inactivation of a histone H3 deacetylase in Calcarisporium arbuscula had led to pleiotropic activation and overexpression of more than 75% o...

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Detalles Bibliográficos
Autores principales: Bai, Jian, Mu, Rong, Dou, Man, Yan, Daojiang, Liu, Bingyu, Wei, Qian, Wan, Jun, Tang, Yi, Hu, Youcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090014/
https://www.ncbi.nlm.nih.gov/pubmed/30109192
http://dx.doi.org/10.1016/j.apsb.2017.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090014/
https://www.ncbi.nlm.nih.gov/pubmed/30109192
http://dx.doi.org/10.1016/j.apsb.2017.12.012

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