Cargando…
Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond
Current approaches have failed to yield success in the translation of neuroprotective therapies from the pre-clinical to the clinical arena for traumatic brain injury (TBI). Numerous explanations have been put forth in both the pre-clinical and clinical arenas. Operation Brain Trauma Therapy (OBTT),...
Autores principales: | Kochanek, Patrick M., Dixon, C. Edward, Mondello, Stefania, Wang, Kevin K. K., Lafrenaye, Audrey, Bramlett, Helen M., Dietrich, W. Dalton, Hayes, Ronald L., Shear, Deborah A., Gilsdorf, Janice S., Catania, Michael, Poloyac, Samuel M., Empey, Philip E., Jackson, Travis C., Povlishock, John T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090020/ https://www.ncbi.nlm.nih.gov/pubmed/30131759 http://dx.doi.org/10.3389/fneur.2018.00640 |
Ejemplares similares
-
Operation Brain Trauma Therapy: An Exploratory Study of Levetiracetam Treatment Following Mild Traumatic Brain Injury in the Micro Pig
por: Lafrenaye, Audrey, et al.
Publicado: (2021) -
Circulating GFAP and Iba-1 levels are associated with pathophysiological sequelae in the thalamus in a pig model of mild TBI
por: Lafrenaye, Audrey D., et al.
Publicado: (2020) -
Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig
por: Lafrenaye, Audrey D., et al.
Publicado: (2015) -
Therapeutic hypothermia and targeted temperature management for traumatic brain injury: Experimental and clinical experience
por: Dietrich, W Dalton, et al.
Publicado: (2017) -
Penetrating Ballistic-Like Brain Injury Leads to MicroRNA Dysregulation, BACE1 Upregulation, and Amyloid Precursor Protein Loss in Lesioned Rat Brain Tissues
por: Thangavelu, Bharani, et al.
Publicado: (2020)