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Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children

Lower respiratory tract infections (LRTI) are often caused by Streptococcus pneumoniae (Spn) and can be recurrent in 8% of children older than 2 years of age. Spn is recognized by pattern-recognition receptors (PRRs) of the innate immune system, in particular toll-like receptors (TLRs) 2 and 4. To a...

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Detalles Bibliográficos
Autores principales:	Siebert, Johan N., Hamann, Lutz, Verolet, Charlotte M., Gameiro, Cécile, Grillet, Stéphane, Siegrist, Claire-Anne, Posfay-Barbe, Klara M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090034/ https://www.ncbi.nlm.nih.gov/pubmed/30131804 http://dx.doi.org/10.3389/fimmu.2018.01780

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