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Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome
Adaptive laboratory evolution (ALE) has emerged as a new approach with which to pursue fundamental biological inquiries and, in particular, new insights into the systemic function of a gene product. Two E. coli knockout strains were constructed: one that blocked the Pentose Phosphate Pathway (gnd KO...
Autores principales: | McCloskey, Douglas, Xu, Sibei, Sandberg, Troy E., Brunk, Elizabeth, Hefner, Ying, Szubin, Richard, Feist, Adam M., Palsson, Bernhard O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090065/ https://www.ncbi.nlm.nih.gov/pubmed/30131786 http://dx.doi.org/10.3389/fmicb.2018.01793 |
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