Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X

Whilst the role of ATF6α in modulating the unfolded protein response (UPR) has been well documented, the function of its paralogue ATF6β is less well understood. Using knockdown in cell culture and gene ablation in mice we have directly compared the roles of ATF6α & β in responding to the increa...

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Detalles Bibliográficos
Autores principales: Forouhan, M., Mori, K., Boot-Handford, R.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090092/
https://www.ncbi.nlm.nih.gov/pubmed/29522813
http://dx.doi.org/10.1016/j.matbio.2018.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090092/
https://www.ncbi.nlm.nih.gov/pubmed/29522813
http://dx.doi.org/10.1016/j.matbio.2018.03.004

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