Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults

We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious Plasmodium falciparum (Pf) sporozoites (SPZ) (PfSPZ Challenge) to try to reduce time and costs of developing PfSPZ Vaccine to prevent malaria in Africa. Immunization with five doses...

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Detalles Bibliográficos
Autores principales: Jongo, Said A., Shekalaghe, Seif A., Church, L. W. Preston, Ruben, Adam J., Schindler, Tobias, Zenklusen, Isabelle, Rutishauser, Tobias, Rothen, Julian, Tumbo, Anneth, Mkindi, Catherine, Mpina, Maximillian, Mtoro, Ali T., Ishizuka, Andrew S., Kassim, Kamaka Ramadhani, Milando, Florence A., Qassim, Munira, Juma, Omar A., Mwakasungula, Solomon, Simon, Beatus, James, Eric R., Abebe, Yonas, KC, Natasha, Chakravarty, Sumana, Saverino, Elizabeth, Bakari, Bakari M., Billingsley, Peter F., Seder, Robert A., Daubenberger, Claudia, Sim, B. Kim Lee, Richie, Thomas L., Tanner, Marcel, Abdulla, Salim, Hoffman, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090339/
https://www.ncbi.nlm.nih.gov/pubmed/29943719
http://dx.doi.org/10.4269/ajtmh.17-1014

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