FOXP3 knockdown inhibits the proliferation and reduces NOTCH1 expression of T cell acute lymphoblastic leukemia cells

OBJECTIVE: Forkhead box P3 (FOXP3) is a master transcriptional factor of regulatory T-cells (Tregs). Recent studies have shown that FOXP3 is associated with growth inhibition of cancer cells. However, the role of FOXP3 in acute T-lymphoblastic leukemia (T-ALL) cells is not known. It was also reporte...

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Detalles Bibliográficos
Autores principales: Yonekura, Satoru, Itoh, Mai, Shiratori, Erika, Ohtaka, Mika, Tohda, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090594/
https://www.ncbi.nlm.nih.gov/pubmed/30103821
http://dx.doi.org/10.1186/s13104-018-3700-3

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