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Real world evaluation of a novel lateral flow assay (AlphaKit® QuickScreen) for the detection of alpha-1-antitrypsin deficiency

BACKGROUND: Alpha-1-Antitrypsin (AAT) deficiency (AATD) is a hereditary disorder that manifests primarily as pulmonary emphysema and liver cirrhosis. The clinically most relevant mutation causing AATD is a single nucleotide polymorphism Glu342Lys (Z-mutation). Despite the recommendation to test ever...

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Detalles Bibliográficos
Autores principales:	Greulich, Timm, Rodríguez-Frias, Francisco, Belmonte, Irene, Klemmer, Andreas, Vogelmeier, Claus F., Miravitlles, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090649/ https://www.ncbi.nlm.nih.gov/pubmed/30103740 http://dx.doi.org/10.1186/s12931-018-0826-8

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