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Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics

BACKGROUND: Specific microRNAs (miRNAs) play essential roles in airway remodeling in asthma. Infection with influenza A virus (IAV) may also magnify pre-existing airway remodeling leading to asthma exacerbation. However, these events remain to be fully defined. We investigated the expression of miRN...

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Detalles Bibliográficos
Autores principales: Moheimani, Fatemeh, Koops, Jorinke, Williams, Teresa, Reid, Andrew T., Hansbro, Philip M., Wark, Peter A., Knight, Darryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090696/
https://www.ncbi.nlm.nih.gov/pubmed/30068332
http://dx.doi.org/10.1186/s12931-018-0851-7

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