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Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study

BACKGROUND: Whilst observational studies establish that lower plasma 25-hydroxyvitamin D (25-OHD) levels are associated with higher risk of colorectal cancer (CRC), establishing causality has proven challenging. Since vitamin D is modifiable, these observations have substantial clinical and public h...

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Detalles Bibliográficos
Autores principales:	He, Yazhou, Timofeeva, Maria, Farrington, Susan M., Vaughan-Shaw, Peter, Svinti, Victoria, Walker, Marion, Zgaga, Lina, Meng, Xiangrui, Li, Xue, Spiliopoulou, Athina, Jiang, Xia, Hyppönen, Elina, Kraft, Peter, Kiel, Douglas P., Hayward, Caroline, Campbell, Archie, Porteous, David, Vucic, Katarina, Kirac, Iva, Filipovic, Masa, Harris, Sarah E., Deary, Ian J., Houlston, Richard, Tomlinson, Ian P., Campbell, Harry, Theodoratou, Evropi, Dunlop, Malcolm G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090711/ https://www.ncbi.nlm.nih.gov/pubmed/30103784 http://dx.doi.org/10.1186/s12916-018-1119-2

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