A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

BACKGROUND: The 2014–2016 Ebola virus (EBOV) outbreak in West Africa highlighted the need for improved therapeutic options against this virus. Approaches targeting host factors/pathways essential for the virus are advantageous because they can potentially target a wide range of viruses, including ne...

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Detalles Bibliográficos
Autores principales: Martin, Scott, Chiramel, Abhilash I., Schmidt, Marie Luisa, Chen, Yu-Chi, Whitt, Nadia, Watt, Ari, Dunham, Eric C., Shifflett, Kyle, Traeger, Shelby, Leske, Anne, Buehler, Eugen, Martellaro, Cynthia, Brandt, Janine, Wendt, Lisa, Müller, Andreas, Peitsch, Stephanie, Best, Sonja M., Stech, Jürgen, Finke, Stefan, Römer-Oberdörfer, Angela, Groseth, Allison, Feldmann, Heinz, Hoenen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090742/
https://www.ncbi.nlm.nih.gov/pubmed/30081931
http://dx.doi.org/10.1186/s13073-018-0570-1

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