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Generation and characterization of UL41 null pseudorabies virus variant in vitro and in vivo

BACKGROUND: The alphaherpesvirus virion host shutoff (vhs) gene, UL41, can induce degradation of host mRNAs and shut off host protein synthesis. The roles of vhs in HSV-1 and HSV-2 have been studied extensively in previous studies, however, relatively little is known about the vhs protein of PRV. ME...

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Detalles Bibliográficos
Autores principales:	Ye, Chao, Chen, Jing, Wang, Tao, Xu, Jingjing, Zheng, Hao, Wu, Jiqiang, Li, Guoxin, Yu, Zhiqing, Tong, Wu, Cheng, Xuefei, Zhou, Shasha, Tong, Guangzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090798/ https://www.ncbi.nlm.nih.gov/pubmed/30071879 http://dx.doi.org/10.1186/s12985-018-1025-4

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