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BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population

BACKGROUND: Ovarian cancer is the leading cause of death worldwide among gynecologic malignancies. The recent approval of inhibitors of poly (ADP-ribose) polymerase (iPARP) in the treatment of ovarian cancer in the presence of a BRCA1/2 mutation has sparked the analysis of women with such diagnosis,...

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Detalles Bibliográficos
Autores principales:	Cardoso, Florencia C., Goncalves, Susana, Mele, Pablo G., Liria, Natalia C., Sganga, Leonardo, Diaz Perez, Ignacio, Podesta, Ernesto J., Solano, Angela R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090818/ https://www.ncbi.nlm.nih.gov/pubmed/30103829 http://dx.doi.org/10.1186/s40246-018-0171-5

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