Cargando…

Cucurbitacin E Inhibits Proliferation and Migration of Intestinal Epithelial Cells via Activating Cofilin

The proliferation and migration of intestinal epithelial cell is important to the barrier integrity of intestinal epithelium. Cucurbitacin E (CuE) is one of the tetracyclic triterpenoids extracted from the cucurbitaceae that has been shown to inhibit cancer cell growth, tumor angiogenesis and inflam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Huapei, Wang, Yu, Li, Li, Sui, Hehuan, Wang, Pei, Wang, Fengjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090878/ https://www.ncbi.nlm.nih.gov/pubmed/30131725 http://dx.doi.org/10.3389/fphys.2018.01090

Ejemplares similares

Cucurbitacin E Induces Autophagy-Involved Apoptosis in Intestinal Epithelial Cells
por: Song, Huapei, et al.
Publicado: (2020)

Activation of Cofilin Increases Intestinal Permeability via Depolymerization of F-Actin During Hypoxia in vitro
por: Song, Huapei, et al.
Publicado: (2019)

Severe Burn-Induced Intestinal Epithelial Barrier Dysfunction Is Associated With Endoplasmic Reticulum Stress and Autophagy in Mice
por: Huang, Yalan, et al.
Publicado: (2018)

Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression
por: Liu, Wen-Bei, et al.
Publicado: (2022)

Analysis of Active Compounds Using Target Protein Cofilin―Cucurbitacins in Cytotoxic Plant Bryonia cretica
por: Nakashima, Souichi, et al.
Publicado: (2022)

Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary target
por: Gabrielsen, Mads, et al.
Publicado: (2013)

Cucurbitacin E inhibits cellular proliferation and enhances the chemo-response in gastric cancer by suppressing AKt activation
por: Si, Wenzhang, et al.
Publicado: (2019)

Antibiotics induced intestinal tight junction barrier dysfunction is associated with microbiota dysbiosis, activated NLRP3 inflammasome and autophagy
por: Feng, Yanhai, et al.
Publicado: (2019)

VASP Activation via the Gα13/RhoA/PKA Pathway Mediates Cucurbitacin-B-Induced Actin Aggregation and Cofilin-Actin Rod Formation
por: Zhang, Yan-Ting, et al.
Publicado: (2014)

Role of Endoplasmic Reticulum Stress-Autophagy Axis in Severe Burn-Induced Intestinal Tight Junction Barrier Dysfunction in Mice
por: Huang, Yalan, et al.
Publicado: (2019)

Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells
por: ZHANG, MENG, et al.
Publicado: (2014)

Cucurbitacin B Inhibits Cell Proliferation by Regulating X-Inactive Specific Transcript Expression in Tongue Cancer
por: Tao, Boqiang, et al.
Publicado: (2021)

Upregulation of LncRNA Malat1 Induced Proliferation and Migration of Airway Smooth Muscle Cells via miR-150-eIF4E/Akt Signaling
por: Lin, Li, et al.
Publicado: (2019)

Simvastatin Downregulates Cofilin and Stathmin to Inhibit Skeletal Muscle Cells Migration
por: Lin, Li-Ping, et al.
Publicado: (2022)

Cucurbitacin E inhibits osteosarcoma cells proliferation and invasion through attenuation of PI3K/AKT/mTOR signalling pathway
por: Wang, Ying, et al.
Publicado: (2016)

Cucurbitacin E Inhibits Huh7 Hepatoma Carcinoma Cell Proliferation and Metastasis via Suppressing MAPKs and JAK/STAT3 Pathways
por: Liu, Yang, et al.
Publicado: (2020)

Cucurbitacins: elucidation of their interactions with the cytoskeleton
por: Wang, Xiaojuan, et al.
Publicado: (2017)

Effects of PAK4/LIMK1/Cofilin‐1 signaling pathway on proliferation, invasion, and migration of human osteosarcoma cells
por: Li, Zhi‐Feng, et al.
Publicado: (2020)

Odorant Receptor 51E2 Agonist β-ionone Regulates RPE Cell Migration and Proliferation
por: Jovancevic, Nikolina, et al.
Publicado: (2017)

Unraveling the Proteomic Landscape of Intestinal Epithelial Cell-Derived Exosomes in Mice
por: Ding, Zhenyu, et al.
Publicado: (2022)

Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway
por: Pang, Dejiang, et al.
Publicado: (2020)

Cofilin activation in pancreatic acinar cells plays a pivotal convergent role for mediating CCK-stimulated enzyme secretion and growth
por: Ramos-Alvarez, Irene, et al.
Publicado: (2023)

Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E
por: Ren, Lingli, et al.
Publicado: (2022)

Reelin Signaling Inactivates Cofilin to Stabilize the Cytoskeleton of Migrating Cortical Neurons
por: Frotscher, Michael, et al.
Publicado: (2017)

Enterotoxigenic Escherichia coli Interferes FATP4-Dependent Long-Chain Fatty Acid Uptake of Intestinal Epithelial Enterocytes via Phosphorylation of ERK1/2-PPARγ Pathway
por: Li, Zhi, et al.
Publicado: (2019)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

Downregulation of LIMK1–ADF/cofilin by DADS inhibits the migration and invasion of colon cancer
por: Su, Jian, et al.
Publicado: (2017)

Correction: Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway
por: Pang, Dejiang, et al.
Publicado: (2023)

Increased Formation of Follicular Antrum in Aquaporin-8-Deficient Mice Is Due to Defective Proliferation and Migration, and Not Steroidogenesis of Granulosa Cells
por: Wang, Dejiang, et al.
Publicado: (2018)

miR-182-5p affects human bladder cancer cell proliferation, migration and invasion through regulating Cofilin 1
por: Wang, Fei, et al.
Publicado: (2019)

Pharmacokinetics and Biological Activity of Cucurbitacins
por: Delgado-Tiburcio, Eugenia Elisa, et al.
Publicado: (2022)

Role of Cofilin in Alzheimer’s Disease
por: Wang, Qiang, et al.
Publicado: (2020)

Modulation of Intestinal Epithelial Cell Proliferation, Migration, and Differentiation In Vitro by Astragalus Polysaccharides
por: Zhang, Chun Li, et al.
Publicado: (2014)

Beneficial Effects of Polysaccharides on the Epithelial Barrier Function in Intestinal Mucositis
por: Sauruk da Silva, Karien, et al.
Publicado: (2021)

Bisecting N-Acetylglucosamine Structures Inhibit Hypoxia-Induced Epithelial-Mesenchymal Transition in Breast Cancer Cells
por: Tan, Zengqi, et al.
Publicado: (2018)

Cucurbitacin B-, E-, and I-Induced Browning of White Adipocytes Is Promoted by the Inhibition of Phospholipase D2
por: Park, Sun Young, et al.
Publicado: (2022)

Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis
por: Li, Peixin, et al.
Publicado: (2018)

Cofilin determines the migration behavior and turning frequency of metastatic cancer cells
por: Sidani, Mazen, et al.
Publicado: (2007)

Sos1 Modulates Extracellular Matrix Synthesis, Proliferation, and Migration in Fibroblasts
por: Fuentes-Calvo, Isabel, et al.
Publicado: (2021)

Inhibition of paclitaxel resistance and apoptosis induction by cucurbitacin B in ovarian carcinoma cells
por: Qu, Yingchun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f1bbcgp26got4aapcq0accgegd