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Genome-wide association study of lung function and clinical implication in heavy smokers

BACKGROUND: The aim of this study is to identify genetic loci associated with post-bronchodilator FEV(1)/FVC and FEV(1), and develop a multi-gene predictive model for lung function in COPD. METHODS: Genome-wide association study (GWAS) of post-bronchodilator FEV(1)/FVC and FEV(1) was performed in 16...

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Detalles Bibliográficos
Autores principales:	Li, Xingnan, Ortega, Victor E., Ampleford, Elizabeth J., Graham Barr, R., Christenson, Stephanie A., Cooper, Christopher B., Couper, David, Dransfield, Mark T., Han, Mei Lan K., Hansel, Nadia N., Hoffman, Eric A., Kanner, Richard E., Kleerup, Eric C., Martinez, Fernando J., Paine, Robert, Woodruff, Prescott G., Hawkins, Gregory A., Bleecker, Eugene R., Meyers, Deborah A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090900/ https://www.ncbi.nlm.nih.gov/pubmed/30068317 http://dx.doi.org/10.1186/s12881-018-0656-z

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