5-hydroxymethylcytosine but not MTAP methylation status can stratify malignant pleural mesothelioma based on the lineage of origin

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis, mainly associated with work or environmental exposure to asbestos. MPM’s molecular profile is largerly unexplored and effective therapies are still lacking. MPM rarely harbours those somatic genetic lesions...

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Detalles Bibliográficos
Autores principales: Bosio, Matteo, Salvaterra, Elena, Datturi, Francesca, Morbini, Patrizia, Zorzetto, Michele, Inghilleri, Simona, Tomaselli, Stefano, Mangiarotti, Patrizia, Meloni, Federica, Cerveri, Isa, Stella, Giulia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090903/
https://www.ncbi.nlm.nih.gov/pubmed/30123503
http://dx.doi.org/10.1186/s40248-018-0137-4

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