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ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

BACKGROUND: To examine the expression of ADAM-17 in rheumatoid arthritis (RA) biological fluids and the role it plays in monocyte adhesion to RA fibroblast-like synoviocytes (FLSs). METHODS: ADAM-17 expression was measured by enzyme-linked immunosorbent assays (ELISAs) in serum from normal (NL) subj...

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Detalles Bibliográficos
Autores principales: Ishii, Sho, Isozaki, Takeo, Furuya, Hidekazu, Takeuchi, Hiroko, Tsubokura, Yumi, Inagaki, Katsunori, Kasama, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090907/
https://www.ncbi.nlm.nih.gov/pubmed/30071898
http://dx.doi.org/10.1186/s13075-018-1657-1