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Removal of pectoral muscle based on topographic map and shape-shifting silhouette

BACKGROUND: In digital mammography, finding accurate breast profile segmentation of women’s mammogram is considered a challenging task. The existence of the pectoral muscle may mislead the diagnosis of cancer due to its high-level similarity to breast body. In addition, some other challenges due to...

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Autores principales: Mughal, Bushra, Muhammad, Nazeer, Sharif, Muhammad, Rehman, Amjad, Saba, Tanzila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090971/
https://www.ncbi.nlm.nih.gov/pubmed/30068304
http://dx.doi.org/10.1186/s12885-018-4638-5
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author Mughal, Bushra
Muhammad, Nazeer
Sharif, Muhammad
Rehman, Amjad
Saba, Tanzila
author_facet Mughal, Bushra
Muhammad, Nazeer
Sharif, Muhammad
Rehman, Amjad
Saba, Tanzila
author_sort Mughal, Bushra
collection PubMed
description BACKGROUND: In digital mammography, finding accurate breast profile segmentation of women’s mammogram is considered a challenging task. The existence of the pectoral muscle may mislead the diagnosis of cancer due to its high-level similarity to breast body. In addition, some other challenges due to manifestation of the breast body pectoral muscle in the mammogram data include inaccurate estimation of the density level and assessment of the cancer cell. The discrete differentiation operator has been proven to eliminate the pectoral muscle before the analysis processing. METHODS: We propose a novel approach to remove the pectoral muscle in terms of the mediolateral-oblique observation of a mammogram using a discrete differentiation operator. This is used to detect the edges boundaries and to approximate the gradient value of the intensity function. Further refinement is achieved using a convex hull technique. This method is implemented on dataset provided by MIAS and 20 contrast enhanced digital mammographic images. RESULTS: To assess the performance of the proposed method, visual inspections by radiologist as well as calculation based on well-known metrics are observed. For calculation of performance metrics, the given pixels in pectoral muscle region of the input scans are calculated as ground truth. CONCLUSIONS: Our approach tolerates an extensive variety of the pectoral muscle geometries with minimum risk of bias in breast profile than existing techniques.
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spelling pubmed-60909712018-08-17 Removal of pectoral muscle based on topographic map and shape-shifting silhouette Mughal, Bushra Muhammad, Nazeer Sharif, Muhammad Rehman, Amjad Saba, Tanzila BMC Cancer Research Article BACKGROUND: In digital mammography, finding accurate breast profile segmentation of women’s mammogram is considered a challenging task. The existence of the pectoral muscle may mislead the diagnosis of cancer due to its high-level similarity to breast body. In addition, some other challenges due to manifestation of the breast body pectoral muscle in the mammogram data include inaccurate estimation of the density level and assessment of the cancer cell. The discrete differentiation operator has been proven to eliminate the pectoral muscle before the analysis processing. METHODS: We propose a novel approach to remove the pectoral muscle in terms of the mediolateral-oblique observation of a mammogram using a discrete differentiation operator. This is used to detect the edges boundaries and to approximate the gradient value of the intensity function. Further refinement is achieved using a convex hull technique. This method is implemented on dataset provided by MIAS and 20 contrast enhanced digital mammographic images. RESULTS: To assess the performance of the proposed method, visual inspections by radiologist as well as calculation based on well-known metrics are observed. For calculation of performance metrics, the given pixels in pectoral muscle region of the input scans are calculated as ground truth. CONCLUSIONS: Our approach tolerates an extensive variety of the pectoral muscle geometries with minimum risk of bias in breast profile than existing techniques. BioMed Central 2018-08-01 /pmc/articles/PMC6090971/ /pubmed/30068304 http://dx.doi.org/10.1186/s12885-018-4638-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Mughal, Bushra
Muhammad, Nazeer
Sharif, Muhammad
Rehman, Amjad
Saba, Tanzila
Removal of pectoral muscle based on topographic map and shape-shifting silhouette
title Removal of pectoral muscle based on topographic map and shape-shifting silhouette
title_full Removal of pectoral muscle based on topographic map and shape-shifting silhouette
title_fullStr Removal of pectoral muscle based on topographic map and shape-shifting silhouette
title_full_unstemmed Removal of pectoral muscle based on topographic map and shape-shifting silhouette
title_short Removal of pectoral muscle based on topographic map and shape-shifting silhouette
title_sort removal of pectoral muscle based on topographic map and shape-shifting silhouette
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090971/
https://www.ncbi.nlm.nih.gov/pubmed/30068304
http://dx.doi.org/10.1186/s12885-018-4638-5
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