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Loureirin B inhibits the proliferation of hepatic stellate cells and the Wnt/β-catenin signaling pathway by regulating miR-148-3p
BACKGROUND: We investigated the activity of loureirin B against liver fibrosis and the underlying molecular mechanisms. METHODS: Hepatic stellate cells (HSCs) from Sprague-Dawley rats were treated with different concentrations of loureirin B. We used the MTT assay to determine HSC proliferation, flo...
Autores principales: | Hu, Jian-Peng, Zhang, Rong, Tang, Min, Li, Yu-Lian, Xun, Lin-Ting, Shi, Zhi-Zhou, An, Ying, Li, Ting, Song, Zheng-Ji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090993/ https://www.ncbi.nlm.nih.gov/pubmed/30123297 http://dx.doi.org/10.1186/s11658-018-0098-9 |
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