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Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. About 90% of ALS cases are without a known genetic cause. The human endogenous retrovirus multi-copy HERV-K(HML-2) group was recently reported to potentially contribute to neurodegeneration and disease pathogenesi...

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Detalles Bibliográficos
Autores principales:	Mayer, Jens, Harz, Christian, Sanchez, Laura, Pereira, Gavin C., Maldener, Esther, Heras, Sara R., Ostrow, Lyle W., Ravits, John, Batra, Ranjan, Meese, Eckart, García-Pérez, Jose Luis, Goodier, John L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091006/ https://www.ncbi.nlm.nih.gov/pubmed/30068350 http://dx.doi.org/10.1186/s13024-018-0275-3

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