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Fibronectin aggregates promote features of a classically and alternatively activated phenotype in macrophages

BACKGROUND: Means to promote endogenous remyelination in multiple sclerosis (MS) benefit from insights into the role of inhibitory molecules that preclude remyelination. Fibronectin assembles into aggregates in MS, which impair oligodendrocyte differentiation and remyelination. Microglia and macroph...

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Detalles Bibliográficos
Autores principales:	Sikkema, Arend H., Stoffels, Josephine M. J., Wang, Peng, Basedow, Frederike J., Bulsink, Robbert, Bajramovic, Jeffrey J., Baron, Wia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091019/ https://www.ncbi.nlm.nih.gov/pubmed/30071854 http://dx.doi.org/10.1186/s12974-018-1238-x

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