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DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936

BACKGROUND: The biological mechanisms underlying frailty in older people are poorly understood. There is some evidence to suggest that DNA methylation patterns may be altered in frail individuals. METHODS: Participants were 791 people aged 70 years from the Lothian Birth Cohort 1936. DNA methylation...

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Detalles Bibliográficos
Autores principales:	Gale, Catharine R., Marioni, Riccardo E., Harris, Sarah E., Starr, John M., Deary, Ian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091041/ https://www.ncbi.nlm.nih.gov/pubmed/30075802 http://dx.doi.org/10.1186/s13148-018-0538-4

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