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TET1 exerts its anti-tumor functions via demethylating DACT2 and SFRP2 to antagonize Wnt/β-catenin signaling pathway in nasopharyngeal carcinoma cells

BACKGROUND: TET1 is a tumor suppressor gene (TSG) that codes for ten-eleven translocation methyl cytosine dioxygenase1 (TET1) catalyzing the conversion of 5-methylcytosine to 5-hydroxy methyl cytosine as a first step of TSG demethylation. Its hypermethylation has been associated with cancer pathogen...

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Detalles Bibliográficos
Autores principales:	Fan, Jiangxia, Zhang, Yan, Mu, Junhao, He, Xiaoqian, Shao, Bianfei, Zhou, Dishu, Peng, Weiyan, Tang, Jun, Jiang, Yu, Ren, Guosheng, Xiang, Tingxiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091063/ https://www.ncbi.nlm.nih.gov/pubmed/30075814 http://dx.doi.org/10.1186/s13148-018-0535-7

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