Expansion and activation of monocytic-myeloid-derived suppressor cell via STAT3/arginase-I signaling in patients with ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease. The dysregulated immune system plays an important role in the pathogenesis of AS. Myeloid-derived suppressor cells (MDSCs) play a key immunoregulatory role in autoimmune arthritis. The aim of this study was to clari...

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Detalles Bibliográficos
Autores principales: Liu, Yu-feng, Zhuang, Kun-hai, Chen, Bin, Li, Pei-wu, Zhou, Xuan, Jiang, Hua, Zhong, Li-mei, Liu, Feng-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091075/
https://www.ncbi.nlm.nih.gov/pubmed/30075733
http://dx.doi.org/10.1186/s13075-018-1654-4

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