Intermittent high glucose-induced oxidative stress modulates retinal pigmented epithelial cell autophagy and promotes cell survival via increased HMGB1

BACKGROUND: In this study, we evaluated the effects of intermittent high glucose on oxidative stress production in retinal pigmented epithelial (RPE) cells and explored whether the mechanisms of autophagy and apoptosis in oxidative stress are associated with high-mobility group box 1 (HMGB1) protein...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Song, Jian, Zhang, Yue, Ma, Yingxue, Yang, Jing, He, Guanghui, Chen, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091182/
https://www.ncbi.nlm.nih.gov/pubmed/30081847
http://dx.doi.org/10.1186/s12886-018-0864-5

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