Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M

Plasmacytoid dendritic cells (pDCs) are a specialized subset of DCs capable of rapidly producing copious amounts of type I IFN (IFN-I) in response to viral infections. The mechanism regulating rapid production of IFN-I after pDCs are exposed to viral nucleic acids remains elusive. Here, we show that...

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Detalles Bibliográficos
Autores principales: Ko, Yi-An, Chan, Yueh-Hsuan, Liu, Chin-Hsiu, Liang, Jian-Jong, Chuang, Tsung-Hsien, Hsueh, Yi-Ping, Lin, Yi-Ling, Lin, Kuo-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091234/
https://www.ncbi.nlm.nih.gov/pubmed/30131810
http://dx.doi.org/10.3389/fimmu.2018.01828

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