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β1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway

OBJECTIVE: To explore the role and mechanism of β1 integrin in the regulation of multicellular drug resistance in hepatocellular carcinoma (HCC). METHODS: This in vitro study used a liquid overlay technique to obtain multicellular spheroids of two human HCC cell lines, HepG2 and Bel-7402. The morpho...

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Detalles Bibliográficos
Autores principales: Tian, Tao, Li, Chun-Li, Fu, Xiao, Wang, Shu-Hong, Lu, Jun, Guo, Hui, Yao, Yu, Nan, Ke-Jun, Yang, Yu-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091828/
https://www.ncbi.nlm.nih.gov/pubmed/29332411
http://dx.doi.org/10.1177/0300060517740807