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β1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway
OBJECTIVE: To explore the role and mechanism of β1 integrin in the regulation of multicellular drug resistance in hepatocellular carcinoma (HCC). METHODS: This in vitro study used a liquid overlay technique to obtain multicellular spheroids of two human HCC cell lines, HepG2 and Bel-7402. The morpho...
Autores principales: | Tian, Tao, Li, Chun-Li, Fu, Xiao, Wang, Shu-Hong, Lu, Jun, Guo, Hui, Yao, Yu, Nan, Ke-Jun, Yang, Yu-Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091828/ https://www.ncbi.nlm.nih.gov/pubmed/29332411 http://dx.doi.org/10.1177/0300060517740807 |
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