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MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila
To discover microRNAs that regulate sleep, we performed a genetic screen using a library of miRNA sponge-expressing flies. We identified 25 miRNAs that regulate baseline sleep; 17 were sleep-promoting and 8 promoted wake. We identified one miRNA that is required for recovery sleep after deprivation...
Autores principales: | Goodwin, Patricia R., Meng, Alice, Moore, Jessie, Hobin, Michael, Fulga, Tudor A., Van Vactor, David, Griffith, Leslie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091868/ https://www.ncbi.nlm.nih.gov/pubmed/29949763 http://dx.doi.org/10.1016/j.celrep.2018.05.078 |
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