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MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila

To discover microRNAs that regulate sleep, we performed a genetic screen using a library of miRNA sponge-expressing flies. We identified 25 miRNAs that regulate baseline sleep; 17 were sleep-promoting and 8 promoted wake. We identified one miRNA that is required for recovery sleep after deprivation...

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Detalles Bibliográficos
Autores principales: Goodwin, Patricia R., Meng, Alice, Moore, Jessie, Hobin, Michael, Fulga, Tudor A., Van Vactor, David, Griffith, Leslie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091868/
https://www.ncbi.nlm.nih.gov/pubmed/29949763
http://dx.doi.org/10.1016/j.celrep.2018.05.078

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