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Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model

While primarily a mosquito-borne virus, Zika virus (ZIKV; genus Flavivirus in the Flaviviridae family) is capable of being sexually transmitted. Thirty to fifty percent of men with confirmed ZIKV infection shed ZIKV RNA in their semen, and prolonged viral RNA shedding in semen can occur for more tha...

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Detalles Bibliográficos
Autores principales: McDonald, Erin M., Duggal, Nisha K., Ritter, Jana M., Brault, Aaron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091970/
https://www.ncbi.nlm.nih.gov/pubmed/30070988
http://dx.doi.org/10.1371/journal.pntd.0006691