The permeation mechanism of organic cations through a CNG mimic channel

Several channels, ranging from TRP receptors to Gap junctions, allow the exchange of small organic solute across cell membrane. However, very little is known about the molecular mechanism of their permeation. Cyclic Nucleotide Gated (CNG) channels, despite their homology with K(+) channels and in co...

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Detalles Bibliográficos
Autores principales: Napolitano, Luisa M. R., Marchesi, Arin, Rodriguez, Alex, De March, Matteo, Onesti, Silvia, Laio, Alessandro, Torre, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091977/
https://www.ncbi.nlm.nih.gov/pubmed/30071012
http://dx.doi.org/10.1371/journal.pcbi.1006295

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