Influence of a Coronary Artery Disease–Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior

OBJECTIVE—: Genome-wide association studies have revealed a robust association between genetic variation on chromosome 15q26.1 and coronary artery disease (CAD) susceptibility; however, the underlying biological mechanism is still unknown. The lead CAD-associated genetic variant (rs17514846) at this...

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Detalles Bibliográficos
Autores principales: Zhao, Guojun, Yang, Wei, Wu, Jingchun, Chen, Bairu, Yang, Xu, Chen, Junhui, McVey, David G., Andreadi, Catherine, Gong, Peng, Webb, Tom R., Samani, Nilesh J., Ye, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092112/
https://www.ncbi.nlm.nih.gov/pubmed/29976768
http://dx.doi.org/10.1161/ATVBAHA.118.311030

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