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Cryo-EM structure of alpha-synuclein fibrils

Parkinson’s disease is a progressive neuropathological disorder that belongs to the class of synucleinopathies, in which the protein alpha-synuclein is found at abnormally high concentrations in affected neurons. Its hallmark are intracellular inclusions called Lewy bodies and Lewy neurites. We here...

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Detalles Bibliográficos
Autores principales:	Guerrero-Ferreira, Ricardo, Taylor, Nicholas MI, Mona, Daniel, Ringler, Philippe, Lauer, Matthias E, Riek, Roland, Britschgi, Markus, Stahlberg, Henning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092118/ https://www.ncbi.nlm.nih.gov/pubmed/29969391 http://dx.doi.org/10.7554/eLife.36402

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