Cargando…

PyMT-1099, a versatile murine cell model for EMT in breast cancer

An epithelial-mesenchymal transition (EMT) has been implicated in cancer metastasis, drug resistance, and in conferring stem cell-like traits to cancer cells. Most studies investigating EMT in cancer have either utilized immortalized or cancer cell lines that are already primed to undergo an EMT and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saxena, Meera, Kalathur, Ravi Kiran Reddy, Neutzner, Melanie, Christofori, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092323/ https://www.ncbi.nlm.nih.gov/pubmed/30108334 http://dx.doi.org/10.1038/s41598-018-30640-1

Ejemplares similares

Author Correction: PyMT-1099, a versatile murine cell model for EMT in breast cancer
por: Saxena, Meera, et al.
Publicado: (2020)

Apc Mutation Enhances PyMT-Induced Mammary Tumorigenesis
por: Prosperi, Jenifer R., et al.
Publicado: (2011)

Py2T Murine Breast Cancer Cells, a Versatile Model of TGFβ-Induced EMT In Vitro and In Vivo
por: Waldmeier, Lorenz, et al.
Publicado: (2012)

Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model
por: Cai, Ying, et al.
Publicado: (2017)

MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model
por: Kwa, Mei Qi, et al.
Publicado: (2021)

A PDE Model of Breast Tumor Progression in MMTV-PyMT Mice
por: Mohammad Mirzaei, Navid, et al.
Publicado: (2022)

Investigating the Role of Heparanase in Breast Cancer Development Utilising the MMTV-PyMT Murine Model of Mammary Carcinoma
por: Jayatilleke, Krishnath M., et al.
Publicado: (2023)

Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model
por: Roselli, Séverine, et al.
Publicado: (2014)

Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model
por: Sirait-Fischer, Evelyn, et al.
Publicado: (2020)

High folic acid diet enhances tumour growth in PyMT-induced breast cancer
por: Hansen, Mariann Fagernæs, et al.
Publicado: (2017)

miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
por: Diepenbruck, Maren, et al.
Publicado: (2017)

Biomarkers of Residual Disease, Disseminated Tumor Cells, and Metastases in the MMTV-PyMT Breast Cancer Model
por: Franci, Christian, et al.
Publicado: (2013)

MicroRNA expression and gene regulation drive breast cancer progression and metastasis in PyMT mice
por: Nogales-Cadenas, Ruben, et al.
Publicado: (2016)

PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development
por: Rumney, Robin M. H., et al.
Publicado: (2017)

Endogenous myoglobin expression in mouse models of mammary carcinoma reduces hypoxia and metastasis in PyMT mice
por: Aboouf, Mostafa A., et al.
Publicado: (2023)

Treatment response assessment with (R)-[(11)CPAQ PET in the MMTV-PyMT mouse model of breast cancer
por: Tegnebratt, T., et al.
Publicado: (2018)

A Milk-Fat Based Diet Increases Metastasis in the MMTV-PyMT Mouse Model of Breast Cancer
por: Velazquez, Fabiola N., et al.
Publicado: (2021)

Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer
por: Velazquez, Fabiola N., et al.
Publicado: (2021)

No Effect of NGAL/lipocalin-2 on Aggressiveness of Cancer in the MMTV-PyMT/FVB/N Mouse Model for Breast Cancer
por: Cramer, Elisabeth P., et al.
Publicado: (2012)

Breast tumors in PyMT transgenic mice expressing mitochondrial catalase have decreased labeling for macrophages and endothelial cells
por: Fatemie, Sy, et al.
Publicado: (2012)

Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer
por: Hallett, Miranda A, et al.
Publicado: (2013)

Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo
por: Attalla, Sherif, et al.
Publicado: (2020)

GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer
por: Lynn, Kristi D, et al.
Publicado: (2010)

Investigating key cell types and molecules dynamics in PyMT mice model of breast cancer through a mathematical model
por: Mohammad Mirzaei, Navid, et al.
Publicado: (2022)

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
por: Decock, Julie, et al.
Publicado: (2015)

Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells
por: Boyle, Sarah T., et al.
Publicado: (2017)

Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential
por: Cordero, Alex, et al.
Publicado: (2023)

High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer
por: Cowen, Sarah, et al.
Publicado: (2015)

Correction to: Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential
por: Cordero, Alex, et al.
Publicado: (2023)

Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors
por: Du, Yi-Chieh Nancy, et al.
Publicado: (2009)

Cholesteryl Ester Promotes Mammary Tumor Growth in MMTV-PyMT Mice and Activates Akt-mTOR Pathway in Tumor Cells
por: Wei, Lengyun, et al.
Publicado: (2021)

Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan
por: Gibby, Krissa, et al.
Publicado: (2012)

The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages
por: Boyle, Sarah T., et al.
Publicado: (2015)

Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model
por: Otsuka, Yutaro, et al.
Publicado: (2018)

Mammary Tumorigenesis and Metabolome in Male Adipose Specific Monocyte Chemotactic Protein-1 Deficient MMTV-PyMT Mice Fed a High-Fat Diet
por: Yan, Lin, et al.
Publicado: (2021)

Deletion of Col15a1 Modulates the Tumour Extracellular Matrix and Leads to Increased Tumour Growth in the MMTV-PyMT Mouse Mammary Carcinoma Model
por: Martínez-Nieto, Guillermo, et al.
Publicado: (2021)

RHAMM regulates MMTV-PyMT-induced lung metastasis by connecting STING-dependent DNA damage sensing to interferon/STAT1 pro-apoptosis signaling
por: Tolg, Cornelia, et al.
Publicado: (2023)

p53 and p16(Ink4a)/p19(Arf) Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells()()
por: Azzopardi, Stephanie, et al.
Publicado: (2016)

Chronic Stress Exposure Suppresses Mammary Tumor Growth and Reduces Circulating Exosome TGF-β Content via β-Adrenergic Receptor Signaling in MMTV-PyMT Mice
por: Dawes, Ryan P, et al.
Publicado: (2020)

S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis
por: Bharadwaj, Alamelu G., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u0lg2vbljo1rtci9o1rp10ca06