Chromatin regulates IL-33 release and extracellular cytokine activity

IL-33 is an epithelium-derived, pro-inflammatory alarmin with enigmatic nuclear localization and chromatin binding. Here we report the functional properties of nuclear IL-33. Overexpression of IL-33 does not alter global gene expression in transduced epithelial cells. Fluorescence recovery after pho...

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Detalles Bibliográficos
Autores principales: Travers, Jared, Rochman, Mark, Miracle, Cora E., Habel, Jeff E., Brusilovsky, Michael, Caldwell, Julie M., Rymer, Jeffrey K., Rothenberg, Marc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092330/
https://www.ncbi.nlm.nih.gov/pubmed/30108214
http://dx.doi.org/10.1038/s41467-018-05485-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092330/
https://www.ncbi.nlm.nih.gov/pubmed/30108214
http://dx.doi.org/10.1038/s41467-018-05485-x

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