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Chromatin regulates IL-33 release and extracellular cytokine activity

IL-33 is an epithelium-derived, pro-inflammatory alarmin with enigmatic nuclear localization and chromatin binding. Here we report the functional properties of nuclear IL-33. Overexpression of IL-33 does not alter global gene expression in transduced epithelial cells. Fluorescence recovery after pho...

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Detalles Bibliográficos
Autores principales:	Travers, Jared, Rochman, Mark, Miracle, Cora E., Habel, Jeff E., Brusilovsky, Michael, Caldwell, Julie M., Rymer, Jeffrey K., Rothenberg, Marc E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092330/ https://www.ncbi.nlm.nih.gov/pubmed/30108214 http://dx.doi.org/10.1038/s41467-018-05485-x

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