Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects

Chromosomal instability (CIN), a high rate of chromosome loss or gain, is often associated with poor prognosis and drug resistance in cancers. Aneuploid, including near-polyploid, cells contain an abnormal number of chromosomes and exhibit CIN. The post-mitotic cell fates following generation of dif...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Qianqian, Au, Bijin, Kulkarni, Madhura, Shen, Yang, Lim, Kah. J., Maimaiti, Jiamila, Wong, Cheng. Kit., Luijten, Monique. N. H., Chong, Han C., Lim, Elaine H., Rancati, Giulia, Sinha, Indrajit, Fu, Zhiyan, Wang, Xiaomeng, Connolly, John. E., Crasta, Karen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092349/
https://www.ncbi.nlm.nih.gov/pubmed/30108207
http://dx.doi.org/10.1038/s41389-018-0072-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092349/
https://www.ncbi.nlm.nih.gov/pubmed/30108207
http://dx.doi.org/10.1038/s41389-018-0072-4

Ejemplares similares