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The induction of the fibroblast extracellular senescence metabolome is a dynamic process

Cellular senescence is often associated with irreparable DNA double strand breaks (IrrDSBs) which accumulate with chronological age (IrrDSBsen). The removal of senescent cells ameliorates several age-related diseases in mice but the translation of these findings into a clinical setting would be aide...

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Detalles Bibliográficos
Autores principales: James, Emma N. L., Bennett, Mark H., Parkinson, E. Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092376/
https://www.ncbi.nlm.nih.gov/pubmed/30108296
http://dx.doi.org/10.1038/s41598-018-29809-5