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The induction of the fibroblast extracellular senescence metabolome is a dynamic process
Cellular senescence is often associated with irreparable DNA double strand breaks (IrrDSBs) which accumulate with chronological age (IrrDSBsen). The removal of senescent cells ameliorates several age-related diseases in mice but the translation of these findings into a clinical setting would be aide...
Autores principales: | James, Emma N. L., Bennett, Mark H., Parkinson, E. Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092376/ https://www.ncbi.nlm.nih.gov/pubmed/30108296 http://dx.doi.org/10.1038/s41598-018-29809-5 |
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