Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time

The circadian clock proteins KaiA, KaiB, and KaiC reconstitute a remarkable circa-24 h oscillation of KaiC phosphorylation that persists for many days in vitro. Here we use high-speed atomic force microscopy (HS-AFM) to visualize in real time and quantify the dynamic interactions of KaiA with KaiC o...

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Detalles Bibliográficos
Autores principales: Mori, Tetsuya, Sugiyama, Shogo, Byrne, Mark, Johnson, Carl Hirschie, Uchihashi, Takayuki, Ando, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092398/
https://www.ncbi.nlm.nih.gov/pubmed/30108211
http://dx.doi.org/10.1038/s41467-018-05438-4

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