Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation

The cerebral cortex underwent rapid expansion and increased complexity during recent hominid evolution. Gene duplications constitute a major evolutionary force, but their impact on human brain development remains unclear. Using tailored RNA sequencing (RNA-seq), we profiled the spatial and temporal...

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Detalles Bibliográficos
Autores principales: Suzuki, Ikuo K., Gacquer, David, Van Heurck, Roxane, Kumar, Devesh, Wojno, Marta, Bilheu, Angéline, Herpoel, Adèle, Lambert, Nelle, Cheron, Julian, Polleux, Franck, Detours, Vincent, Vanderhaeghen, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092419/
https://www.ncbi.nlm.nih.gov/pubmed/29856955
http://dx.doi.org/10.1016/j.cell.2018.03.067

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