A cancer vaccine approach for personalized treatment of Lynch Syndrome

Lynch syndrome (LS) is a cancer predisposition disorder wherein patients have a 70–80% lifetime risk of developing colorectal cancers (CRC). Finding germline mutations in predisposing genes allows for risk assessment of CRC development. Here we report a germline heterozygous frame-shift mutation in...

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Detalles Bibliográficos
Autores principales: Majumder, Snigdha, Shah, Rakshit, Elias, Jisha, Manoharan, Malini, Shah, Priyanka, Kumari, Anjali, Chakraborty, Papia, Kode, Vasumathi, Mistry, Yogesh, Coral, Karunakaran, Mittal, Bharti, SM, Sakthivel Murugan, Mahadevan, Lakshmi, Gupta, Ravi, Chaudhuri, Amitabha, Khanna-Gupta, Arati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092430/
https://www.ncbi.nlm.nih.gov/pubmed/30108227
http://dx.doi.org/10.1038/s41598-018-30466-x

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