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REST overexpression in mice causes deficits in spontaneous locomotion

Overexpression of REST has been implicated in brain tumors, ischemic insults, epilepsy, and movement disorders such as Huntington’s disease. However, owing to the lack of a conditional REST overexpression animal model, the mechanism of action of REST overexpression in these disorders has not been es...

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Detalles Bibliográficos
Autores principales: Lu, Li, Marisetty, Anantha, Liu, Bin, Kamal, Mohamed Mostafa, Gumin, Joy, Veo, Bethany, Cai, YouQing, Kassem, Dina Hamada, Weng, Connie, Maynard, Mark E., Hood, Kimberly N., Fuller, Gregory N., Pan, Zhizhong Z., Cykowski, Matthew D., Dash, Pramod K., Majumder, Sadhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092433/
https://www.ncbi.nlm.nih.gov/pubmed/30108242
http://dx.doi.org/10.1038/s41598-018-29441-3