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Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1

Recent work has demonstrated that transmembrane channel-like 1 protein (TMC1) is an essential component of the sensory transduction complex in hair cells of the inner ear. A closely related homolog, TMC2, is expressed transiently in the neonatal mouse cochlea and can enable sensory transduction in T...

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Detalles Bibliográficos
Autores principales: Asai, Yukako, Pan, Bifeng, Nist-Lund, Carl, Galvin, Alice, Lukashkin, Andrei N., Lukashkina, Victoria A., Chen, Tianwen, Zhou, Wu, Zhu, Hong, Russell, Ian J., Holt, Jeffrey R., Géléoc, Gwenaelle S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092434/
https://www.ncbi.nlm.nih.gov/pubmed/30108254
http://dx.doi.org/10.1038/s41598-018-28958-x