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Single-Fluorescent Protein Reporters Allow Parallel Quantification of Natural Killer Cell-Mediated Granzyme and Caspase Activities in Single Target Cells

Natural killer (NK) cells eliminate infected and tumorigenic cells through delivery of granzymes via perforin pores or by activation of caspases via death receptors. In order to understand how NK cells combine different cell death mechanisms, it is important to quantify target cell responses on a si...

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Detalles Bibliográficos
Autores principales:	Liesche, Clarissa, Sauer, Patricia, Prager, Isabel, Urlaub, Doris, Claus, Maren, Eils, Roland, Beaudouin, Joël, Watzl, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092488/ https://www.ncbi.nlm.nih.gov/pubmed/30135688 http://dx.doi.org/10.3389/fimmu.2018.01840

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