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Integrated imaging of [(11)C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy (1)H-MRS in amyotrophic lateral sclerosis

OBJECTIVE: To determine the relationship between brain tissue metabolites measured by in vivo magnetic resonance spectroscopy ((1)H-MRS), and glial activation assessed with [(11)C]-PBR28 uptake in people with amyotrophic lateral sclerosis (ALS). METHODS: Forty ALS participants were evaluated clinica...

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Detalles Bibliográficos
Autores principales:	Ratai, Eva-Maria, Alshikho, Mohamad J., Zürcher, Nicole R., Loggia, Marco L., Cebulla, Catherine L., Cernasov, Paul, Reynolds, Beverly, Fish, Jennifer, Seth, Raghav, Babu, Suma, Paganoni, Sabrina, Hooker, Jacob M., Atassi, Nazem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092554/ https://www.ncbi.nlm.nih.gov/pubmed/30112276 http://dx.doi.org/10.1016/j.nicl.2018.08.007

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