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Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3
Signal transducer and activator of transcription 3 (STAT3) is an attractive therapeutic target for cancer treatment. In this study, we identify lycorine is an effective inhibitor of STAT3, leading to repression of multiple oncogenic processes in colon carcinoma. Lycorine selectively inactivates phos...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092588/ https://www.ncbi.nlm.nih.gov/pubmed/30135654 http://dx.doi.org/10.3389/fphar.2018.00881 |