Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3

Signal transducer and activator of transcription 3 (STAT3) is an attractive therapeutic target for cancer treatment. In this study, we identify lycorine is an effective inhibitor of STAT3, leading to repression of multiple oncogenic processes in colon carcinoma. Lycorine selectively inactivates phos...

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Detalles Bibliográficos
Autores principales: Wu, Song, Qiu, Yuling, Shao, Yingying, Yin, Shuangshuang, Wang, Rui, Pang, Xu, Ma, Junhong, Zhang, Chunze, Wu, Bo, Koo, Sangho, Han, Lifeng, Zhang, Yi, Gao, Xiumei, Wang, Tao, Yu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092588/
https://www.ncbi.nlm.nih.gov/pubmed/30135654
http://dx.doi.org/10.3389/fphar.2018.00881

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